Irritable Bowel Syndrome (IBS)

Background of IBS

Irritable Bowel Syndrome (IBS)

Type

Clinical features

Possible pathogenesis of IBS

Alteration in fecal microflora

Altered colonic motility

Hypersensitivity of visceral Gi receptors in response to stimuli

Intestinal mucosal inflammation in some patients

Psychosocial dysfunction

Associated conditions

Chronic fatigue syndrome (systemic exertion intolerance disease)

Fibromyalgia

Functional dyspepsia

GERD

Non-cardiac chest pain

Psychiatric conditions

- Major depression

- Anxiety

- Somatization

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